Bernadett Bacsa

(Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University Graz, Austria)

Prof. Klaus Groschner and his team from the University of Graz study the photophamacological control of TRPC3/6 in T-lymphocytes. They achieve this by analyzing novel reporter for TRPC activity (R/K-GECO fusion proteins) and their recently developed benzimidazole actuators (OptoBI-1) of TRCP3. This precise regulation of T cell activity bears high potential for therapeutic strategies.